Module 3 Quiz


Test Your Knowledge

Choose the best answer based on your reading of Module 3

  1. The ability to differentiate into any of these three layers (endoderm, mesoderm, endoderm) but not into cells of the placenta is called:
    1. Pluripotency
    2. Tumorogenesis
    3. Plasticity
    4. Self-renewal

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  2. Why can’t pluripotent stem cells develop into fetus?
    1. They really can if implanted into a uterus of a very young female
    2. Because they do not have the correct hormones to stimulate them to form a fetus
    3. Because they lack the potential to generate extra-embryonic tissue, such as the placenta
    4. None of the above

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  3. How do you classify a specialized cell?
    1. Based on the cell surface proteins that it expresses
    2. Only on its morphology and functional properties
    3. Its capacity to generate progeny like itself
    4. Based on the genes that are turned off or on in the cell
    5. All of the above

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  4. What property of the cell do transcription factors and epigenetic enzymes regulate?
    1. Plasticity
    2. Stemness
    3. Pluripotency
    4. All of the above

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  5. Define epigenetics.
    1. The process by which a cell becomes increasingly specialized and matures into a more distinct form and function
    2. The study of the mechanism by which heritable changes in a phenotype occur in the absence of any alterations in the DNA sequence of base pairs
    3. How cells adapt to their environment by altering their genetic composition
    4. None of the above

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  6. Whose theory does epigenetics remind one of?
    1. Charles Darwin
    2. Jean-Baptiste Lamarck
    3. Robert Hooke
    4. Theodor Schwaan

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  7. Which pathways co-regulate the balance between pluripotency and lineage-specific differentiation in stem cells?
    1. Posttranslational modifications of the histones
    2. DNA methylation
    3. Both 1 and 2
    4. None of the above

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  8. Which of the following statements is true?
    1. In ES cells, high CpG promoter has high DNA methylation levels
    2. In ES cells, high CpG promoter has low DNA methylation levels
    3. In ES cells, low CpG promoter has relatively high DNA methylation levels
    4. Both 2 and 3 are correct

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